Be Ready for Lipid Rescue in Drug Toxicity
You’ll see orders for lipid emulsion (Intralipid, etc) to treat toxicity from local anesthetics (bupivacaine, lidocaine, etc).
Local anesthetics are becoming more popular, since they can reduce the need to use opioids for pain. But they have serious risks...such as low blood pressure, heart arrhythmias, and seizures.
Lipids can reduce “local anesthetic systemic toxicity” (LAST)...partly by binding to the med.
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