Some Patients Will Take Antidepressant Combos

You may raise an eyebrow if a patient has more than one antidepressant on their home med list.

But fewer than half of patients with depression get desired effects from just one first-line med...such as an SSRI (fluoxetine, sertraline, etc) or SNRI (duloxetine, venlafaxine, etc).

And there’s no “best” next step.

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