Simplify IV N-Acetylcysteine for Acetaminophen Overdoses
February 2025
Recent FDA approval for 2-step IV dosing is opening a bag of questions around using N-acetylcysteine (NAC) for acetaminophen overdose.
Acetaminophen poisonings are common. Poison control centers handled over 80,000 US cases in 2023.
NAC is the antidote...and has been used for decades. It deactivates a toxic acetaminophen metabolite that can cause deadly liver failure.
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