OTC Brand-Name Extensions

Full update July 2021

This chart contains selected OTC products and may not be all-inclusive. Products that contain the expected primary ingredient(s) (in addition to other ingredients) have generally not been included. Availability of products and formulations are subject to change.

-Information in the chart below comes from current U.S. and Canadian product labeling.-

Selected OTC Product Lines

Expected Primary Ingredient(s)

Actual Primary Ingredient(s)

Examples of U.S. Brand Extensions

Alka-Seltzer

Aspirin

There are many different formulations of Alka-Seltzer that contain aspirin PLUS additional ingredients that are not listed here.

The following products have acetaminophen with other ingredients but no aspirin:

Alka-Seltzer Plus Maximum Strength Cold & Cough Liquid GelsAlka-Seltzer Plus Maximum Strength Day Cold & Flu Liquid GelsAlka-Seltzer Plus Maximum Strength Day and Night Cold & Flu Liquid GelsAlka-Seltzer Plus Severe Cold & Flu PowerFast Fizz, Alka-Seltzer Plus Maximum Strength Severe SinusAllergy & Cough Liquid Gels, Alka-Seltzer Plus Maximum Strength Severe Sinus Congestion & Cough Liquid GelsAlka-Seltzer Plus Maximum Strength Cold & Cough Liquid GelsAlka-Seltzer Plus Severe CoughMucus & Congestion Liquid GelsAlka-Seltzer Plus Severe SinusCold & Cough Liquid Gels.

These products contain no aspirin or acetaminophen:

Alka-Seltzer GoldAlka-Seltzer Heartburn Plus Gas ReliefChewsAlka-Seltzer Ultra Strength Heartburn ReliefChewsAlka-Seltzer Extra Strength Heartburn ReliefChewsAlka-Seltzer Cool Action Heartburn Relief gum, Alka-Seltzer Heartburn effervescent tabs.

Cepacol

Benzocaine and menthol (lozenges)

Dyclonine and glycerin (spray)

Cepacol Sore Throat and Cough and Cepacol Extra Strength Sore Throat and Cough lozenges have benzocaine and dextromethorphan.

Cepacol mouthwash has cetylpyridinium chloride.

Chloraseptic

Benzocaine and menthol (lozenges and strips)

Phenol (spray)

Chloraseptic Warming Sore Throat lozenges have benzocaine.

Chloraseptic Total Sore Throat and Cough lozenges have benzocaine, menthol, and dextromethorphan.

Desenex

Undecylenate

Desenex topical powder has miconazole.

Dramamine

Dimenhydrinate

Dramamine Less Drowsy tablets, Dramamine All Day LD chewable tablets, and Dramamine – N Nausea have meclizine.

Dramamine Non-Drowsy Naturals has ginger root.

Dulcolax

Bisacodyl

Dulcolax Stool Softener liquid gels and softgels have docusate.

Dulcolax Soft Chews and Dulcolax liquid have magnesium hydroxide.

Excedrin

Acetaminophen, aspirin, and caffeine

Excedrin Tension Headache products have acetaminophen and caffeine.

Excedrin PM Headache has acetaminophen, aspirin, and diphenhydramine.

Lotrimin AF

Clotrimazole

Lotrimin Ultra Jock Itch and Lotrimin Ultra Athlete’s Foot topical creams have butenafine.

Lotrimin AF powder and sprays have miconazole.

Lotrimin Daily Prevention Deo spray has tolnaftate.

Lotrimin Daily Sweat and Odor Control powder has topical starch powder.

Midol

Acetaminophen and pamabrom

Midol PM has acetaminophen and diphenhydramine.

Midol Complete has acetaminophen, caffeine, and pyrilamine.

Midol Long Lasting Relief caplets have acetaminophen.

Monistat

Miconazole

Monistat Care Instant Itch Relief spray has benzocaine.

Monistat Complete Care Chafing Relief gel has dimethicone.

Monistat Complete Care Instant Itch Relief cream has hydrocortisone.

Monistat Tioconazole 1 ointment has tioconazole.

Monistat Care Stay Fresh Feminine Freshness Gel has polycarbophil, glycerin, mineral oil, etc.

Mucinex

Guaifenesin

Mucinex Nightshift Cold & Flu liquid has acetaminophen, dextromethorphan, triprolidine, and NO guaifenesin.

Mucinex Maximum Strength Nightshift Severe Cold & Flu, Mucinex Nightshift Cold & Flu Clear & Cool, and Mucinex Children’s Free From Multi-System Cold & Flu Nighttime have acetaminophen, dextromethorphan, phenylephrine, triprolidine, and NO guaifenesin.

Mucinex Sinus-Max Severe Nasal Congestion Relief Clear & Cool and Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy nasal sprays have oxymetazoline.

Mucinex Maximum Strength Fast-Max Night Cold & Flu liquid gels and Mucinex Maximum Strength Sinus-Max Night liquid and liquid gels have acetaminophen, dextromethorphan, doxylamine, phenylephrine, and NO guaifenesin.

Mucinex Children’s Night Time Multi-Symptom Cold, Mucinex Maximum Strength Sinus-Max Night caplets, and Mucinex Maximum Strength Fast-Max Night Time Cold & Flu caplets have acetaminophen, diphenhydramine, phenylephrine, and NO guaifenesin.

Mylanta

Aluminum and magnesium hydroxides with or without simethicone

Mylanta Gas Minis have simethicone.

Mylanta Coat and Cool and Mylanta Tonight liquid have calcium carbonate, magnesium hydroxide, and simethicone.

Pepto-Bismol

Bismuth subsalicylate

Pepto-Kids chewable tabs have calcium carbonate.

Robitussin

Guaifenesin

Children’s Robitussin Cough Long-Acting, Robitussin Long-Acting CoughGels, Children’s Robitussin
12-Hour Cough Relief
, Robitussin 12-Hour Cough Relief, and Robitussin Lingering Cold Long-Acting CoughGels and liquid have dextromethorphan.

Children’s Robitussin Nighttime Cough DM and Robitussin Maximum Strength Nighttime Cough DM have dextromethorphan and doxylamine.

Robitussin Severe Cough plus Sore Throat has acetaminophen and dextromethorphan.

Children’s Robitussin Nighttime Cough Long-Acting DM and Robitussin Children’s Cough & Cold Long-Acting has dextromethorphan and chlorpheniramine.

Robitussin Honey Severe Cough, Flu plus Sore Throat Nighttime has acetaminophen and diphenhydramine.

Robitussin Severe Multi-Symptom Cough, Cold & Flu Nighttime has acetaminophen, diphenhydramine, and phenylephrine.

Salonpas patches

Camphor, menthol, and methyl salicylate

Salonpas Lidocaine Pain Relieving Patch has lidocaine.

Salonpas Lidocaine Plus Cream has lidocaine and benzyl alcohol.

Salonpas Pain Relieving Jet SpraySalonpas Pain Relief Patch, and Salonpas Arthritis Pain patches have menthol and methyl salicylate.

Salonpas Pain Relieving Gel-Patch Hot has capsaicin and menthol.

Salonpas Pain Relieving Patch Hot has capsaicin.

Salonpas gel has diclofenac.

Sudafed

Pseudoephedrine

Sudafed PE Sinus Pressure plus Pain has acetaminophen and phenylephrine.

Sudafed PE Head Congestion plus Mucus has acetaminophen, guaifenesin, and phenylephrine.

Sudafed PE Nighttime Sinus Congestion has diphenhydramine and phenylephrine.

Sudafed PE Head Congestion plus Flu Severe has acetaminophen, dextromethorphan, guaifenesin, and phenylephrine.

Children’s Sudafed PE and Sudafed PE Sinus Congestion have phenylephrine.

Children’s Sudafed PE Cold plus Cough has dextromethorphan and phenylephrine.

Sudafed PE Head Congestion plus Pain has ibuprofen and phenylephrine.

Unisom

Doxylamine

Unisom PM Pain caplets have acetaminophen and diphenhydramine.

Unisom SleepGelsSleepMinis, and SleepMelts have diphenhydramine.

Unisom Simple Slumber gummies have melatonin.

Visine

Tetrahydrozoline

Visine for Contacts has an isotonic borate buffer, glycerin, and hypromellose.

Visine Dry Eye ReliefVisine Dry Eye Relief Tired Eye, and Visine Dry Eye Relief All Day Comfort have polyethylene glycol.

Visine Allergy Eye Relief Multi-Action has naphazoline and pheniramine.

Zantac

Ranitidine (no longer available)

Zantac 360° and Maximum Strength Zantac 360° have famotidine.

Examples of Canadian Brand Extensions

Benylin

Dextromethorphan and guaifenesin

Benylin Sore Throat lozenges have benzocaine.

Benylin Extra Strength All-In-One Cold, Flu & Cough Night caplets have pseudoephedrine, acetaminophen, and diphenhydramine.

Benylin Extra Strength Chest Congestion & Cold, Benylin Extra Strength Mucus & Phlegm syrup, and Benylin Extra Strength Sore Throat & Cough have guaifenesin and menthol.

Benylin Dry Cough Night and Benylin Night for Children Cough has diphenhydramine.

Benylin Extra Strength Cold and Sinus Day tablets have acetaminophen and phenylephrine.

Benylin Extra Strength Cold and Sinus Plus tablets have acetaminophen, chlorpheniramine, and phenylephrine.

Benylin for Children All-in-One Cold and Fever Nighttime syrup has acetaminophen, dextromethorphan, and diphenhydramine.

Benylin for Children All-in-One Cold and Fever has acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine.

Benylin Extra Strength Dry Cough and Benylin for Children Dry Cough syrups have dextromethorphan.

Benylin for Children Cough and Cold syrup has dextromethorphan and pseudoephedrine.

Cepacol

Benzocaine and menthol

Cepacol Sensations and Children’s Cepacol lozenges have dichlorobenzyl alcohol and amylmetacresol.

Cepacol Sensations Sore Throat & Cough has dichlorobenzyl alcohol, amylmetacresol, and menthol.

Cepacol Sensations Sore Throat & Blocked Nose has dichlorobenzyl alcohol, amylmetacresol, and levomenthol.

Chloraseptic

Benzocaine

Chloraseptic Max Sore Throat Relief spray and lozenges have phenol and glycerin.

Chloraseptic Sore Throat Spray has phenol.

Claritin

Loratadine

Claritin Nasal Spray has oxymetazoline.

Midol

Acetaminophen and pamabrom

Menstrual Midol Complete has acetaminophen, caffeine, and pyrilamine.

Pepto-Bismol

Bismuth subsalicylate

Children’s Pepto has calcium carbonate.

Robitussin

Guaifenesin

Robitussin Total Cough, Cold, & Flu liquid has acetaminophen, dextromethorphan, and pseudoephedrine.

Robitussin Total Cough, Cold, & Flu Extra Strength Nighttime liquid has acetaminophen, chlorpheniramine, dextromethorphan, and pseudoephedrine.

Robitussin DM CoughGels have dextromethorphan.

Robitussin Children’s Cough and Cold liquid has dextromethorphan and pseudoephedrine.

Robitussin Children’s Cold liquid has phenylephrine and brompheniramine.

Robitussin Children’s Cough & Cold Bedtime has dextromethorphan, brompheniramine, and phenylephrine.

Robitussin Honey Cough & Cold Nighttime has dextromethorphan and doxylamine.

Unisom-2

Doxylamine

Unisom SleepGels and Unisom tablets have diphenhydramine.

Visine

Tetrahydrozoline

Visine dry eye Tired Eye Relief have glycerin and hypromellose.

Visine allergy Advance with Antihistamine has naphazoline and pheniramine.

Cite this document as follows: Clinical Resource, OTC Brand-Name Extensions.  Pharmacist’s Letter/Prescriber’s Letter. July 2021.  [370709]

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